Dra. Mariela Fernanda Pérez



Cargo
Investigadora Independiente CONICET - Profesora Titular UNC

Contact
mfperez@unc.edu.ar

Líneas de investigación
I. Identificación de Mecanismos y Estructuras Cerebrales Involucrados en los Efectos Conductuales de Fármacos Psicoactivos y Evaluación de Nuevas Estrategias Terapéuticas para el Tratamiento de la Adicción o Dependencia. II. Implementación de Nuevas Tecnologías para el Abordaje Farmacológico del Tratamiento de Patologías Centrales e Identificación de Nuevos Blancos Farmacológicos para el Diseño de Nuevos Fármacos

Publicaciones de los últimos 5 años

Montivero AJ, Ghersi MS, Silvero C MJ, Artur de la Villarmois E, Catalan-Figueroa J, Herrera M, Becerra MC, Hereñú CB and Pérez MF. EARLY IGF-1 GENE THERAPY PREVENTED OXIDATIVE STRESS AND COGNITIVE DEFICITS INDUCED BY TRAUMATIC BRAIN INJURY. Front. Pharmacol. 12:672392. 2021. doi: 10.3389/fphar.2021.672392.

Catalan-Figueroa J, García MA, Contreras P, Boisset CB, Gonzalez PM, Fiedler JL, Pérez MF, Morales JO. POLOXAMER 188-COATED AMMONIUM METHACRYLATE COPOLYMER NANOCARRIERS ENHANCE LOPERAMIDE PERMEABILITY ACROSS PGP-EXPRESSING EPITHELIA. Mol Pharm. 2020 Oct 12. doi: 10.1021/acs.molpharmaceut.0c00623. Epub ahead of print. PMID: 33044825.

Sebastian O. Siri, Victoria Rozés-Salvador, Emilce Artur de la Villarmois, Marisa S.Ghersi, Gonzalo Quassollo, Mariela F. Pérez and Cecilia Conde. DECREASE OF RAB11 PREVENTS THE CORRECT DENDRITIC ARBORIZATION, SYNAPTIC PLASTICITY AND SPATIAL MEMORY FORMATION. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research, Volume 1867, Issue 9, September 2020, 118735. https://doi.org/10.1016/j.bbamcr.2020.118735.

Macarena L. Herrera, Romina Deza-Ponzio, Marisa S. Ghersi, Emilce A. de la Villarmois, Miriam B. Virgolini, Mariela F. Perez, Victor A. Molina, Marıa J. Bellini and Claudia B. Hereñú. EARLY COGNITIVE IMPAIRMENT BEHIND NIGRO-STRIATAL CIRCUIT NEUROTOXICITY: ARE ASTROCYTES INVOLVED? ASN Neuro, first Published May 28, 2020. https://doi.org/10.1177/1759091420925977.

Emilce Artur de la Villarmois, Laura A. Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B. Schiöth, Valeria P. Carlini and Mariela F. Perez. PHARMACOLOGICAL NOS-1 INHIBITION WITHIN THE HIPPOCAMPUS PREVENTED EXPRESSION OF COCAINE SENSITIZATION: CORRELATION WITH REDUCED SYNAPTIC TRANSMISSION. Molecular Neurobiology Agosto 2019. DOI : 10.1007/s12035-019-01725-3. [Epub ahead of print].

Emilce Artur de la Villarmois and Mariela F. Pérez. COGNITIVE INTERFERENCE AS A POSSIBLE THERAPEUTIC STRATEGY TO PREVENT EXPRESSION OF BENZODIAZEPINE WITHDRAWAL. European Journal of Neuroscience. Eur J Neurosci. 2019 Jul 12. doi: 10.1111/ejn.14515. [Epub ahead of print].

Lucila de Bortoli da Silva, Débora da Luz Scheffer, Felipe José de Matos, Karina Ghisoni, Rita Raisman-Vozari, Aderbal Aguiar Junior, Raymond Mongeau, Laurence Lanfumey-Mongrédien, Renata T. Nesi, Paulo Oliveira, Rui Prediger, Marisa Ghersi, Laura Gabach, Mariela F. Pérez, Susana de Barioglio, Ananda Christina Staats Pires, Roberta Martins and Alexandra Latini. TETRAHYDROBIOPTERIN IMPROVES HIPPOCAMPAL NITRIC OXIDE-LINKED LONG-TERM MEMORY. Molecular Genetics and Metabolism. 2018 Sep;125(1-2):104-111. doi: 10.1016/j.ymgme.2018.06.003. Epub 2018 Jun 11.

Silvero C. MJ, Rocca DM, Artur de la Villarmois E, Fournier K, Lanterna AE, Pérez MF, Becerra MC, Scaiano JC. SELECTIVE PHOTOINDUCED ANTIBACTERIAL ACTIVITY OF AMOXICILLIN-COATED GOLD NANOPARTICLES: FROM ONE-STEP SYNTHESIS TO IN VIVO CYTOCOMPATIBILITY. ACS OMEGA. 2018, 3; 1220−1230.

Vallejo M, Carlini V, Gabach L, Ortega MG, L Cabrera J, de Barioglio SR, Pérez M, Agnese AM. SAUROXINE REDUCES MEMORY RETENTION IN RATS AND IMPAIRS HIPPOCAMPAL LONG-TERM POTENTIATION GENERATION. Biomed Pharmacother. 2017 Apr 27; 91:155-161. doi: 10.1016/j.biopha.2017.04.016.

Marchese NA, Paz MC, Caeiro X, Dadam FM, Baiardi G, Perez MF, Bregonzio C. ANGIOTENSIN II AT1 RECEPTORS MEDIATE NEURONAL SENSITIZATION AND SUSTAINED BLOOD PRESSURE RESPONSE INDUCED BY A SINGLE INJECTION OF AMPHETAMINE Neuroscience. 2017 Jan 6; 340:521-529. doi: 10.1016/j.neuroscience.2016.11.006.

Karina Ghisoni, Filipe Carvalho Matheus, Paulo Alexandre de Oliveira, Rui Prediger, Laura Gabach, Mariela F. Perez, Valeria P. Carlini, LuizBarbeito, Aderbal Aguiar, Laurence Lanfumey, Alexandra Latini. NEOPTERIN ACTS AS AN ENDOGENOUS COGNITIVE ENHANCER. Brain Behav Immun. 2016 Feb 23. pii: S0889-1591(16)30039-3. doi: 10.1016/j.bbi.2016.02.019. [Epub ahead of print].

María Belén Poretti, Rahul S Sawant, Mathias Rask-Andersen, Marta Fiol de Cuneo, Helgi B. Schiöth, Mariela F. Perez*, Valeria Paola Carlini*. REDUCED VASOPRESSIN RECEPTORS ACTIVATION MEDIATES THE ANTI-DEPRESSANT EFFECTS OF FLUOXETINE AND VENLAFAXINE IN BULBECTOMY MODEL OF DEPRESSION.*Joint last and corresponding authors. Psychopharmacology, 2016 Mar; 233(6):1077-86. doi: 10.1007/s00213-015-4187-4. Epub 2015 Dec 23.

Natalia Andrea Marchese*,EmilceArtur de la Villarmois*,Martin Basmadjian, Mariela Fernanda Perez#, Gustavo Baiardi, Claudia Bregonzio. BRAIN ANGIOTENSIN II AT1 RECEPTORS ARE INVOLVED IN THE ACUTE AND LONG-TERM AMPHETAMINE-INDUCED NEUROCOGNITIVE ALTERATIONS. *Joint first authors, #corresponding author. Psychopharmacology, 2016 Mar;233(5):795-807. doi: 10.1007/s00213-015-4153-1. Epub 2015 Nov 28.

Capítulos de libro

Emilce Artur de la Villarmois, María Florencia Constantin and Mariela F. Pérez. FROM BENZODIAZEPINE PRESCRIPTION TO DEPENDENDENCE: LEARNING PROCESSES INVOLVED. In Psychiatry and Neuroscience Update – Vol. IV: From Epistemology to Clinical Psychiatry. Editors: Gargiulo Pascual Angel y Mesones Arroyo Humberto Luis. Springer, 2020.

Agustin J. Montivero, Marisa S. Ghersi, Johanna Catalán-Figueroa, Lina Formica, Nahuel Camacho, Antonella F. Culasso, Claudia B. Hereñú, Santiago D. Palma and Mariela F. Pérez. BEYOND ACUTE TRAUMATIC BRAIN INJURY: MOLECULAR IMPLICATIONS OF ASSOCIATED NEURO INFLAMMATION IN HIGHER-ORDER COGNITIVE PROCESSES. In Psychiatry and Neuroscience Update – Vol. IV: Vol. IV: From Epistemology to Clinical Psychiatry. Editors: Gargiulo Pascual Angel y Mesones Arroyo Humberto Luis. Springer, 2020.

Bregonzio Claudia, Marchese Natalia Andrea, Paz Maria Constanza, Artur de la Villarmois Emilce, Baiardi Gustavo, Pérez Mariela Fernanda. THE EXTENT OF NEUROADAPTIVE RESPONSES TO PSYCHOSTIMULANTS: FOCUS ON BRAIN ANGIOTENSIN SYSTEM. In Psychiatry and Neuroscience Update – Vol. II: A Translational Approach. Editors: Gargiulo Pascual Angel y Mesones Arroyo Humberto Luis. Springer, 2016.

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