Dra. Rosana Crespo

Investigadora Independiente CONICET - Profesora Asistente UNC


Líneas de investigación
Efecto Neuroprotector de Aceites Esenciales en un Modelo Parkinsoniano de Neurodegeneración Nigro-estriatal con 6-OH Dopamina

Publicaciones de los últimos 5 años

Zappa Villar, M. F., López Hanotte, J., Crespo, R., Pardo, J., & Reggiani, P. C. (2021). Insulin‐like growth factor 1 gene transfer for sporadic Alzheimer’s disease: New evidence for trophic factor mediated hippocampal neuronal and synaptic recovery‐based behavior improvement. Hippocampus, 31(10), 1137-1153. https://doi.org/10.1002/hipo.23379

Rodenak-Kladniew, B., Castro, M. A., Crespo, R., Galle, M., & de Bravo, M. G. (2020). Anti-cancer mechanisms of linalool and 1, 8-cineole in non-small cell lung cancer A549 cells. Heliyon, 6(12), e05639. https://doi.org/10.1016/j.heliyon.2020.e05639

Castro, M. A., Llanos, M. A., Rodenak-Kladniew, B. E., Gavernet, L., Galle, M. E., & Crespo, R. (2020). Citrus reticulata peel oil as an antiatherogenic agent: Hypolipogenic effect in hepatic cells, lipid storage decrease in foam cells, and prevention of LDL oxidation. Nutrition, Metabolism and Cardiovascular Diseases, 30(9), 1590-1599. https://doi.org/10.1016/j.numecd.2020.04.033

Crespo, R., Rodenak-Kladniew, B. E., Castro, M. A., Soberón, M. V., & Lavarías, S. M. (2020). Induction of oxidative stress as a possible mechanism by which geraniol affects the proliferation of human A549 and HepG2 tumor cells. Chemico-biological interactions, 320, 109029. https://doi.org/10.1016/j.cbi.2020.109029

Rodenak-Kladniew, B., Castro, A., Stärkel, P., Galle, M., & Crespo, R. (2020). 1, 8-Cineole promotes G0/G1 cell cycle arrest and oxidative stress-induced senescence in HepG2 cells and sensitizes cells to anti-senescence drugs. Life sciences, 243, 117271. https://doi.org/10.1016/j.lfs.2020.117271

Julio, L. M., Copado, C. N., Crespo, R., Diehl, B. W., Ixtaina, V. Y., & Tomás, M. C. (2019). Design of microparticles of chia seed oil by using the electrostatic layer-by-layer deposition technique. Powder Technology, 345, 750-757. https://doi.org/10.1016/j.powtec.2019.01.047

Rodenak-Kladniew, B., Castro, A., Stärkel, P., De Saeger, C., de Bravo, M. G., & Crespo, R. (2018). Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways. Life sciences, 199, 48-59. https://doi.org/10.1016/j.lfs.2018.03.006

Castro, M. A., Rodenak-Kladniew, B., Massone, A., Polo, M., de Bravo, M. G., & Crespo, R. (2018). Citrus reticulata peel oil inhibits non-small cell lung cancer cell proliferation in culture and implanted in nude mice. Food & function, 9(4), 2290-2299. https://doi.org/10.1039/C7FO01912B

Montero-Villegas, S., Crespo, R., Rodenak-Kladniew, B., Castro, M. A., Galle, M., Cicció, J. F., … & Polo, M. (2018). Cytotoxic effects of essential oils from four Lippia alba chemotypes in human liver and lung cancer cell lines. Journal of EssEntial oil rEsEarch, 30(3), 167-181. https://doi.org/10.1080/10412905.2018.1431966

Zappa-Villar, M. F., López-León, M., Pardo, J., Costa, M., Crespo, R., Dardenne, M., … & Reggiani, P. C. (2017). A new adenovector system for implementing thymulin gene therapy for inflammatory disorders. Molecular immunology, 87, 180-187. https://doi.org/10.1016/j.molimm.2017.04.014

Crespo, R., Wei, K., Rodenak-Kladniew, B., Mercola, M., Ruiz-Lozano, P., & Hurtado, C. (2017). Effect of geraniol on rat cardiomyocytes and its potential use as a cardioprotective natural compound. Life sciences, 172, 8-12. https://doi.org/10.1016/j.lfs.2017.01.008

Montero-Villegas, S., Polo, M., Galle, M., Rodenak-Kladniew, B., Castro, M., Ves-Losada, A., Crespo, R*. & de Bravo, M. G. (2017). Inhibition of mevalonate pathway and synthesis of the storage lipids in human liver-derived and non-liver cell lines by Lippia alba essential oils. Lipids, 52(1), 37-49. DOI: 10.1007/s11745-016-4218-x

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